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Discussion The main results of this study are that (1) Niclosamide has a pH-dependent solubility and dissolution rate, and (2) solubility and the amount of niclosamide in supernatant solution is determined by the nature of the solid form in contact with the supernatant solution and ultimately the most thermodynamically stable crystalline forms

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When assessing changes in HbA1c, there was a significant reduction in these levels seen after 32 weeks of treatment in comparison to baseline levels in the experimental groups receiving a combined treatment